Clofazimine and QT prolongation in the treatment of rifampicin-resistant tuberculosis: Findings of aDSM in Taiwan

Clofazimine was significantly associated with an increased risk of QTcF prolongation. QTcF≥501ms was potentially associated with fatal event and needed to be managed cautiously.

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Institutions

Publication Details

Journal
Journal of Microbiology Immunology and Infection
Published
2024-08-09
DOI
https://doi.org/10.1016/j.jmii.2024.08.002
Citations
11
Primary Topic
Cardiac electrophysiology and arrhythmias
Type
article
Field-Weighted Citation Impact
4.42
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article

Clofazimine and QT prolongation in the treatment of rifampicin-resistant tuberculosis: Findings of aDSM in Taiwan

Chen‐Yuan Chiang, Jen‐Jyh Lee, Yi-Wen Huang, Chou-Jui Lin et al.
11 citations
Journal of Microbiology Immunology and Infection
Cardiac electrophysiology and arrhythmias
4.42
article

Clofazimine and QT prolongation in the treatment of rifampicin-resistant tuberculosis: Findings of aDSM in Taiwan

Chen‐Yuan Chiang, Jen‐Jyh Lee, Yi-Wen Huang, Chou-Jui Lin, Jinhua Chen, Chih‐Hsin Lee, Ming-Chih Yu, Chih‐Bin Lin, Shun-Tien Chien
article en
11 citations

Abstract

Clofazimine was significantly associated with an increased risk of QTcF prolongation. QTcF≥501ms was potentially associated with fatal event and needed to be managed cautiously.

Journal of Microbiology Immunology and InfectionVol. 57(5)
Tzu Chi University (TW), Taipei Medical University Hospital (TW), Tao Yuan General Hospital (TW), Ministry of Health and Welfare (TW), International Union Against Tuberculosis and Lung Disease (FR), Chest Hospital, Ministry of Health and Welfare (TW), Wan Fang Hospital (TW), Chang Hua Hospital (TW), Taipei Medical University (TW), Chung Shan Medical University (TW)
Good health and well-being
Openalex Percentile: Top 5%
Cardiac electrophysiology and arrhythmias
4.42
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