Photoredox/Copper Dual-Catalyzed Phosphorothiolation of Propargylic Derivatives for the Switchable Synthesis of <i>S</i>-Alkyl, <i>S</i>-Vinyl and <i>S</i>-Allenyl Phosphorothioates
Herein, we report a photoredox/copper dual-catalyzed selective phosphorothiolation of propargylic derivatives from easily accessible [P(O)SH] compounds. This reaction provides a general, mild and versatile procedure to synthesize a variety of synthetically useful <i>S</i>-alkyl, <i>S</i>-vinyl and <i>S</i>-allenyl phosphorothioates selectively from the same set of simple starting materials.
Authors
- Yuzhen Gao (ORCID: https://orcid.org/0000-0002-2690-7407)
- Shiwei Yang (ORCID: https://orcid.org/0000-0001-6593-5235)
- Bin Zheng (ORCID: https://orcid.org/0000-0003-2636-4120)
- Hu Chen (ORCID: https://orcid.org/0000-0002-5958-9361)
- Hua‐Ze Dong
- Jinmiao Zhu (ORCID: https://orcid.org/0000-0002-0641-1711)
- Shanshan Shi (ORCID: https://orcid.org/0000-0002-0959-1607)
- Hong‐Yu Ren (ORCID: https://orcid.org/0000-0003-4733-7607)
- Zhaoyang Liang
- Xiaohong Wang
Institutions
- Hefei Normal University (CN)
- Chinese Academy of Sciences (CN)
- Fujian Institute of Research on the Structure of Matter (CN)
Publication Details
- Journal
- Organic Letters
- Published
- 2024-08-09
- DOI
- https://doi.org/10.1021/acs.orglett.4c02636
- Citations
- 15
- Primary Topic
- Sulfur-Based Synthesis Techniques
- Type
- article
- Field-Weighted Citation Impact
- 3.75
Funders
- National Natural Science Foundation of China
- Hefei Normal University
- Anhui Provincial Department of Education