Probabilistic Refinement of Focused Ultrasound Thalamotomy Targeting for Parkinson's Disease Tremor
We demonstrated that the most effective MRgFUS thalamotomy target in TDPD is in the ventral intermediate nucleus/ventralis oralis posterior border region. This finding offers new insights into the thalamic regions instrumental in tremor control, with pivotal implications for improving treatment outcomes. © 2024 The Author(s). Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.
Authors
- Jürgen Germann (ORCID: https://orcid.org/0000-0003-0995-8226)
- Kazuaki Yamamoto (ORCID: https://orcid.org/0000-0001-7362-6707)
- Cletus Cheyuo (ORCID: https://orcid.org/0000-0002-9717-3738)
- Michael L. Schwartz (ORCID: https://orcid.org/0000-0001-5244-1666)
- Vibhor Krishna (ORCID: https://orcid.org/0000-0002-4141-4192)
- Suneil K. Kalia (ORCID: https://orcid.org/0000-0003-2054-1915)
- Yuri Ferreira Felloni Borges (ORCID: https://orcid.org/0000-0002-0724-1136)
- Alfonso A. Fasano (ORCID: https://orcid.org/0000-0001-5346-0180)
- Artur Vetkas (ORCID: https://orcid.org/0000-0002-4487-432X)
- Andrés M. Lozano (ORCID: https://orcid.org/0000-0001-8257-3694)
- Mojgan Hodaie (ORCID: https://orcid.org/0000-0001-6278-4929)
- Can Sarica (ORCID: https://orcid.org/0000-0001-8419-7426)
- Zion Zibly (ORCID: https://orcid.org/0000-0003-1718-0821)
- W. Jeffrey Elias
Institutions
- University of North Carolina at Chapel Hill (US)
- Lahey Hospital and Medical Center (US)
- Sunnybrook Health Science Centre (CA)
- University Health Network (CA)
- University of Toronto (CA)
- Toronto Western Hospital (CA)
- University of Virginia Health System (US)
- Sheba Medical Center (IL)
- Lahey Medical Center (US)
- Krembil Foundation (CA)
- Krembil Research Institute
- Osaka University of Pharmaceutical Sciences (JP)
Publication Details
- Journal
- Movement Disorders
- Published
- 2024-08-09
- DOI
- https://doi.org/10.1002/mds.29965
- Citations
- 13
- Primary Topic
- Neurological disorders and treatments
- Type
- article
- Field-Weighted Citation Impact
- 4.80
Funders
- University of Toronto