Ru(II)‐Catalyzed C8 Alkenylation of Isoquinolones with Allyl Alcohol

Abstract A simple Ru(II)‐catalyzed protocol for the alkenylation of isoquinolones with readily accessible allyl alcohols to generate aldehyde bearing isoquinolones has been developed. The use of green solvent like dimethyl carbonate makes this method environment‐friendly. Experimental studies were carried out to support the proposed mechanism. The reaction was scaled up to showcase the application of the current method.

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Publication Details

Journal
Asian Journal of Organic Chemistry
Published
2024-08-09
DOI
https://doi.org/10.1002/ajoc.202400407
Citations
4
Primary Topic
Asymmetric Hydrogenation and Catalysis
Type
article
Field-Weighted Citation Impact
0.63
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article

Ru(II)‐Catalyzed C8 Alkenylation of Isoquinolones with Allyl Alcohol

Upendra Sharma, XXXXXXX Manisha, Tamanna Sharma
4 citations
Asian Journal of Organic Chemistry
Asymmetric Hydrogenation and Catalysis
0.63
article

Ru(II)‐Catalyzed C8 Alkenylation of Isoquinolones with Allyl Alcohol

Upendra Sharma, XXXXXXX Manisha, Tamanna Sharma
article en
4 citations

Abstract

Abstract A simple Ru(II)‐catalyzed protocol for the alkenylation of isoquinolones with readily accessible allyl alcohols to generate aldehyde bearing isoquinolones has been developed. The use of green solvent like dimethyl carbonate makes this method environment‐friendly. Experimental studies were carried out to support the proposed mechanism. The reaction was scaled up to showcase the application of the current method.

Asian Journal of Organic ChemistryVol. 13(12)
Institute of Himalayan Bioresource Technology (IN), Academy of Scientific and Innovative Research (IN)
Life in Land
Openalex Percentile: Top 37%
Asymmetric Hydrogenation and Catalysis
0.63
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