Sodium Hypophosphite as a Halogen Atom Transfer (XAT) Agent under Photocatalytic Conditions
The ability of sodium hypophosphite to generate the phosphorus-centered radical, which can activate the carbon-halogen bond via the halogen atom transfer (XAT) is described. The hydroalkylation of nonactivated alkenes with methyl bromoacetate was performed using sodium hypophosphite as reducing agent under photocatalytic conditions. The key phosphorus centered radical is formed from the hypophosphite anion by hydrogen atom abstraction.
Authors
- Vladislav S. Kostromitin
- Vitalij V. Levin (ORCID: https://orcid.org/0000-0002-5606-8085)
- Alexander D. Dilman (ORCID: https://orcid.org/0000-0001-8048-7223)
- Demian Y. Cheboksarov
- Ekaterina V. Malakhova
Institutions
- D. Mendeleyev University of Chemical Technology of Russia (RU)
- Lomonosov Moscow State University (RU)
- N.D. Zelinsky Institute of Organic Chemistry (RU)
Publication Details
- Journal
- The Journal of Organic Chemistry
- Published
- 2024-08-09
- DOI
- https://doi.org/10.1021/acs.joc.4c01412
- Citations
- 7
- Primary Topic
- Radical Photochemical Reactions
- Type
- article
- Field-Weighted Citation Impact
- 1.75
Funders
- Ministry of Science and Higher Education of the Russian Federation