Outcomes of inadequate empiric therapy and timing of newer antibacterial therapy in hospitalized adults with culture-positive Enterobacterales and Pseudomonas aeruginosa: a multicenter analysis
Overall, IET and delayed use of newer antibacterials are associated with significantly worse hospital outcomes. More rapid identification of high-risk patients can facilitate adequate therapy and timely use of newer antibacterials developed for resistant Gram-negative pathogens.
Authors
- Vikas Gupta (ORCID: https://orcid.org/0000-0001-5291-5446)
- John Lock
- ChinEn Ai
- Todd Riccobene (ORCID: https://orcid.org/0000-0002-3702-1097)
- Kalvin Yu (ORCID: https://orcid.org/0000-0003-4651-2012)
- Gang Ye (ORCID: https://orcid.org/0000-0003-0369-7942)
- Sara Gregory
Institutions
- Becton Dickinson (United States) (US)
- AbbVie (United States) (US)
Publication Details
- Journal
- BMC Infectious Diseases
- Published
- 2024-08-09
- DOI
- https://doi.org/10.1186/s12879-024-09700-7
- Citations
- 14
- Primary Topic
- Antibiotic Use and Resistance
- Type
- article
- Field-Weighted Citation Impact
- 4.17
Funders
- AbbVie