The Antidepressant Effects of Vaporized <i>N</i> , <i>N</i> -Dimethyltryptamine: An Open-Label Pilot Trial in Treatment-Resistant Depression
The rapid onset and sustained antidepressant effects of vaporized DMT align with the paradigm of rapid-acting antidepressants to be used in the scope of interventional psychiatry. The noninvasive route and short-acting nature of DMT offer practical advantages, potentially enhancing accessibility to psychedelic treatments.Clinical Trial Registration: Clinicaltrials.gov NCT06094907.
Authors
- Fernanda Palhano-Fontes (ORCID: https://orcid.org/0000-0002-1612-6703)
- Dráulio Barros de Araújo (ORCID: https://orcid.org/0000-0002-6934-2485)
- Raíssa Nóbrega de Almeida (ORCID: https://orcid.org/0000-0003-3687-8790)
- Daniel Montanini
- Nicole Leite Galvão‐Coelho (ORCID: https://orcid.org/0000-0002-4887-8635)
- Isabel Wießner (ORCID: https://orcid.org/0000-0003-1653-2565)
- Ewerton Teixeira
- Sérgio Ruschi Bergamachi Silva (ORCID: https://orcid.org/0000-0003-0677-0439)
- Marcelo Falchi-Carvalho (ORCID: https://orcid.org/0000-0002-7407-880X)
- Érica J. Pantrigo (ORCID: https://orcid.org/0000-0003-3649-6207)
- Raynara Bolcont (ORCID: https://orcid.org/0000-0001-9376-3979)
- José V Costa-Macedo
- Flávia Arichelle
- Rodrigo Florence-Vilela
- Rosana K. A. de Macedo
- Sophie Laborde (ORCID: https://orcid.org/0009-0000-0192-713X)
- Emerson Arcoverde
- Handersson Barros
- D. Barbosa (ORCID: https://orcid.org/0009-0005-3947-577X)
Institutions
- Centro Universitário FEI (BR)
- Universidade Federal do Rio Grande do Norte (BR)
- Hospital Universitário Onofre Lopes (BR)
Publication Details
- Journal
- Psychedelic Medicine
- Published
- 2024-08-09
- DOI
- https://doi.org/10.1089/psymed.2024.0002
- Citations
- 13
- Primary Topic
- Psychedelics and Drug Studies
- Type
- article
- Field-Weighted Citation Impact
- 8.31