Sensory Profiles Predict Symptoms of Central Sensitization in Low Back Pain: A Predictive Model Research Study

<b>Background</b>: Acute low back pain has a high prevalence, and when persisting into chronicity, it results in enormous socio-economic consequences. Sensory preferences may be key factors in predicting central sensitization as the main mechanism of nociplastic pain and chronicity. <b>Objectives</b>: Build a model to predict central sensitization symptoms using sensory profiles based on the PROGRESS framework. <b>Methods</b>: A Prognostic Model Research study was carried out to predict central sensitization symptoms at 12 weeks, using baseline sensory profiles, based on 114 patients with acute low back pain. Independent variables were sensory profiles, state and trait anxiety, age, duration, pain severity, depressive symptoms, and pain catastrophizing. <b>Results</b>: This model, based on continuous data, significantly predicts central sensitization symptoms at 12 weeks. It contains two significantly contributing variables: sensory profile Sensory Sensitive (unstandardized B-value = 0.42; <i>p</i> = 0.01) and trait anxiety (unstandardized B-value = 0.53; <i>p</i> ≤ 0.001). The model has a predictive value of R² = 0.38. <b>Conclusions</b>: This model significantly predicts central sensitization symptoms based on sensory profile Sensory Sensitive and trait anxiety. This model may be a useful tool to intervene in a bottom-up and top-down approaches to prevent chronicity in clinical practice, including individual sensory preferences and behavioral responses to sensory stimulation in rehabilitation strategies.