Exposure to Lead in Drinking Water Causes Cognitive Impairment via an Alzheimer’s Disease Gene-Dependent Mechanism in Adult Mice
These results raise the possibility that the increased risk of dementia associated with Pb exposure in adults may be tied to its subsequent interaction with either pre-existing or developing AD-related neuropathology.
Authors
- Alex M. Helman
- Misty M. Hobbs (ORCID: https://orcid.org/0000-0002-1594-0797)
- Katharina Köhler (ORCID: https://orcid.org/0000-0003-1919-0193)
- Jason M. Unrine (ORCID: https://orcid.org/0000-0003-3012-5261)
- Caitlin R. Wessel (ORCID: https://orcid.org/0000-0001-8154-9721)
- Tina L. Beckett
- Dana M. Niedowicz (ORCID: https://orcid.org/0000-0002-1052-898X)
- Teresa Macheda
- Christopher Infantino
- Antonela Rodriguez
- Lindsey Farris
- M. Tyler Maisel
- Michael P. Murphy (ORCID: https://orcid.org/0000-0003-3079-0659)
Institutions
- University of Kentucky (US)
Publication Details
- Journal
- Journal of Alzheimer s Disease
- Published
- 2024-08-09
- DOI
- https://doi.org/10.3233/jad-240640
- Citations
- 3
- Primary Topic
- Heavy Metal Exposure and Toxicity
- Type
- article
- Field-Weighted Citation Impact
- 0.94
Funders
- National Science Foundation
- National Institutes of Health