Screening of Lithium Substituted Ag-TiO<sub>2</sub> Nanoparticle Coating for Antibiofilm Application

Bacterial infections and biofilm growth are common mishaps associated with medical devices, and they contribute significantly to ill health and mortality. Removal of bacterial deposition from these devices is a major challenge, resulting in an immediate necessity for developing antibacterial coatings on the surfaces of medical implants. In this context, we developed an innovative coating strategy that can operate at low temperatures (80 °C) and preserve the devices' integrity and functionality. An innovative Ag-TiO<sub>2</sub> based coating was developed by ion exchange between silver nitrate (AgNO<sub>3</sub>) and lithium titanate (Li<sub>4</sub>Ti<sub>5</sub>O<sub>12</sub>) on glass substrates for different periods, ranging from 10 to 60 min. The differently coated samples were tested for their antibacterial and antibiofilm efficacy.

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Publication Details

Journal
ACS Applied Bio Materials
Published
2024-08-09
DOI
https://doi.org/10.1021/acsabm.4c00711
Citations
2
Primary Topic
Bone Tissue Engineering Materials
Type
article
Field-Weighted Citation Impact
0.37

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article

Screening of Lithium Substituted Ag-TiO2 Nanoparticle Coating for Antibiofilm Application

Sumit Manna, Bhola Nath Pal, Sobhan Hazra, Lipi Pradhan et al.
2 citations
ACS Applied Bio Materials
Bone Tissue Engineering Materials
0.37
article

Screening of Lithium Substituted Ag-TiO2 Nanoparticle Coating for Antibiofilm Application

Sumit Manna, Bhola Nath Pal, Sobhan Hazra, Lipi Pradhan, Sudip Mukherjee
article en
2 citations

Abstract

Bacterial infections and biofilm growth are common mishaps associated with medical devices, and they contribute significantly to ill health and mortality. Removal of bacterial deposition from these devices is a major challenge, resulting in an immediate necessity for developing antibacterial coatings on the surfaces of medical implants. In this context, we developed an innovative coating strategy that can operate at low temperatures (80 °C) and preserve the devices' integrity and functionality. An innovative Ag-TiO<sub>2</sub> based coating was developed by ion exchange between silver nitrate (AgNO<sub>3</sub>) and lithium titanate (Li<sub>4</sub>Ti<sub>5</sub>O<sub>12</sub>) on glass substrates for different periods, ranging from 10 to 60 min. The differently coated samples were tested for their antibacterial and antibiofilm efficacy.

ACS Applied Bio MaterialsVol. 7(9)
Indian Institute of Technology BHU (IN), Banaras Hindu University (IN)
Department of Biotechnology, Ministry of Science and Technology, India, Department of Science and Technology, Ministry of Science and Technology, India, Indian Council of Medical Research, University Grants Commission, Ministry of Education, India, Indian Institute of Technology (BHU) Varanasi, Science and Engineering Research Board
Openalex Percentile: Top 44%
Bone Tissue Engineering Materials
0.37
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