A transcription factor of SHI family AaSHI1 activates artemisinin biosynthesis genes in Artemisia annua
Overall, a genome-wide analysis of the AaSHI TF family of A. annua was conducted. Five AaSHIs were identified in A. annua genome. Among the identified AaSHIs, AaSHI1 was found to be localized to the nucleus and activate the expression of structural genes of artemisinin biosynthesis including AaADS and AaCYP71AV1. These results indicated that AaSHI1 had positive roles in modulating artemisinin biosynthesis, providing candidate genes for obtaining high-quality new A. annua germplasms.
Authors
- Yinkai Yang
- Guoyin Kai (ORCID: https://orcid.org/0000-0001-7586-9067)
- Yongpeng Li (ORCID: https://orcid.org/0000-0002-8995-311X)
- Tsubasa Shoji (ORCID: https://orcid.org/0000-0002-6917-3773)
- Xiaolong Hao (ORCID: https://orcid.org/0000-0002-9176-8052)
- Jin Li (ORCID: https://orcid.org/0000-0003-2875-3314)
- Pengyang Li (ORCID: https://orcid.org/0000-0001-7202-574X)
- Qin Zhou (ORCID: https://orcid.org/0000-0002-6078-5722)
- Miaomiao Sheng (ORCID: https://orcid.org/0000-0002-1422-0595)
- Xiaojing Ma (ORCID: https://orcid.org/0009-0001-8303-6660)
Institutions
- Zhejiang Chinese Medical University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- University of Toyama (JP)
Publication Details
- Journal
- BMC Genomics
- Published
- 2024-08-09
- DOI
- https://doi.org/10.1186/s12864-024-10683-7
- Citations
- 3
- Primary Topic
- Plant biochemistry and biosynthesis
- Type
- article
- Field-Weighted Citation Impact
- 0.70
Funders
- National Natural Science Foundation of China
- China Postdoctoral Science Foundation
- Zhejiang Chinese Medical University
- National Key Research and Development Program of China
- Natural Science Foundation of Zhejiang Province