Causal relationship between circulating levels of cytokines and bone mineral density: A mendelian randomization study
Our MR analyses indicated a causal effect between two circulating cytokines and BMD at corresponding sites (HGF and HE-BMD, MIP-1α and TB-BMD), along with suggestive evidence of a potential causality between seven cytokines and BMD at the corresponding sites. These findings would provide insights into the prevention and treatment of osteoporosis, especially immunoporosis.
Authors
- Chao Li (ORCID: https://orcid.org/0000-0002-1950-0190)
- Xian Zhang (ORCID: https://orcid.org/0000-0002-6055-0130)
- Yitao Liao
- Taichuan Xu
Institutions
- Nanjing University of Chinese Medicine (CN)
- Wuxi Taihu Hospital (CN)
- Wuxi People's Hospital (CN)
Publication Details
- Journal
- Cytokine
- Published
- 2024-08-09
- DOI
- https://doi.org/10.1016/j.cyto.2024.156729
- Citations
- 4
- Primary Topic
- Bone Metabolism and Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.94