Genomic Determinants of Outcome in Acute Lymphoblastic Leukemia
Genetic subtype, patterns of aneuploidy, and secondary genomic alterations determine risk of relapse in childhood ALL. Comprehensive genomic analysis is required for optimal risk stratification.
Authors
- Wanda L. Salzer (ORCID: https://orcid.org/0000-0002-7820-9635)
- Zhongshan Cheng (ORCID: https://orcid.org/0000-0002-6746-5182)
- Karen R. Rabin (ORCID: https://orcid.org/0000-0002-4081-8195)
- Mignon L. Loh (ORCID: https://orcid.org/0000-0003-4099-4700)
- Brent Lee Wood (ORCID: https://orcid.org/0000-0001-7414-3969)
- Eric Larsen (ORCID: https://orcid.org/0000-0002-4783-5975)
- Ching‐Hon Pui (ORCID: https://orcid.org/0000-0003-0303-5658)
- Gang Wu (ORCID: https://orcid.org/0000-0003-4379-7964)
- Stephen P. Hunger (ORCID: https://orcid.org/0000-0002-5492-3957)
- Mary Shago (ORCID: https://orcid.org/0000-0002-7386-2504)
- Elizabeth A. Raetz (ORCID: https://orcid.org/0000-0002-8547-1658)
- Pradyuamna Baviskar (ORCID: https://orcid.org/0000-0003-1110-5695)
- Anne Angiolillo
- Chunxu Qu
- Sima Jeha (ORCID: https://orcid.org/0000-0003-2835-5869)
- Charles Grenfell Mullighan (ORCID: https://orcid.org/0000-0002-1871-1850)
- Jeremy Wang (ORCID: https://orcid.org/0000-0002-0673-9418)
- Nilsa C. Ramirez (ORCID: https://orcid.org/0000-0002-9945-9449)
- Naomi Joan Winick (ORCID: https://orcid.org/0000-0002-6636-3870)
- Wenan Chen (ORCID: https://orcid.org/0000-0003-0379-2368)
- Ilaria Iacobucci (ORCID: https://orcid.org/0000-0003-2008-1365)
- Cheryl L. Willman (ORCID: https://orcid.org/0000-0002-1524-2622)
- Stanley Pounds (ORCID: https://orcid.org/0000-0002-9167-2114)
- Abdelrahman Elsayed (ORCID: https://orcid.org/0000-0003-4610-4297)
- Leonard A. Mattano (ORCID: https://orcid.org/0000-0002-8409-0589)
- Ti‐Cheng Chang (ORCID: https://orcid.org/0000-0001-5302-9147)
- Richard C. Harvey (ORCID: https://orcid.org/0000-0002-4904-9767)
- Andrew J. Carroll (ORCID: https://orcid.org/0000-0001-9844-730X)
- Michael J. Burke (ORCID: https://orcid.org/0000-0001-6626-2773)
- Kelly W. Maloney (ORCID: https://orcid.org/0000-0002-3711-9529)
- William L. Carroll (ORCID: https://orcid.org/0000-0003-1550-4167)
- Meenakshi Devidas (ORCID: https://orcid.org/0000-0002-1099-3478)
- Cheng Cheng (ORCID: https://orcid.org/0000-0002-9910-8294)
- I‐Ming Chen (ORCID: https://orcid.org/0000-0001-7759-6648)
- Michael J. Borowitz
- Nyla A. Heerema
- Dale J. Hedges
Institutions
- University of North Carolina at Chapel Hill (US)
- University of Southern California (US)
- Seattle Children's Hospital (US)
- St. Jude Children's Research Hospital (US)
- Nationwide Children's Hospital (US)
- Mayo Clinic (US)
- Children's Hospital of Philadelphia (US)
- Children's National (US)
- Children's Hospital of Los Angeles (US)
- Johns Hopkins University (US)
- Uniformed Services University of the Health Sciences (US)
- University of New Mexico (US)
- Baylor College of Medicine (US)
- University of Toronto (CA)
- University of Washington (US)
- Medical College of Wisconsin (US)
- University of Alabama at Birmingham (US)
- NYU Langone Health (US)
- New England Cancer Specialists (US)
- Children's Hospital Colorado (US)
- Mayo Clinic in Arizona (US)
- NYU Langone’s Laura and Isaac Perlmutter Cancer Center
- University of Colorado Anschutz Medical Campus (US)
- The Ohio State University (US)
- University of Pennsylvania (US)
- The University of Texas Southwestern Medical Center (US)
- University of Colorado Denver (US)
Publication Details
- Journal
- Journal of Clinical Oncology
- Published
- 2024-08-09
- DOI
- https://doi.org/10.1200/jco.23.02238
- Citations
- 48
- Primary Topic
- Acute Lymphoblastic Leukemia research
- Type
- article
- Field-Weighted Citation Impact
- 26.06
Funders
- St. Baldrick's Foundation
- Children's Hospital of Philadelphia
- Nationwide Children's Hospital
- Seattle Children's Research Institute
- American Lebanese Syrian Associated Charities
- Broad Institute
- National Institutes of Health
- National Cancer Institute
- School of Medicine, University of North Carolina at Chapel Hill
- Moonshot Research and Development Program
- Cancer Moonshot