Recurrent Desmoplastic Infantile Ganglioglioma Treated with Antineoplastons: Partial Response and Overall Survival of > 11.8 Years in a Ten-Month-Old Female

Desmoplastic infantile tumors (DIT) are rare neoplasms of the central nervous system that occur in infants and young children. According to the World Health Organization (WHO) grading system, DIT are classified into three subtypes: Desmoplastic infantile astrocytoma (DIA), desmoplastic infantile ganglioglioma (DIG), and desmoplastic/nodular medulloblastoma (DNMB). DIA and DIG are WHO grade 1 while DNMB is WHO grade 4. Recurrent WHO grade 1 DIT have a very poor prognosis and there is no standardized therapy.