Preparation of Benzo[<i>a</i>]fluorenes via Pd-Catalyzed Annulation of 5-(2-Bromophenyl)pent-3-en-1-ynes
A palladium-promoted cascade cyclization of 5-(2-bromophenyl)pent-3-en-1-ynes is developed for the synthesis of benzo[<i>a</i>]fluorene derivatives. The reaction proceeds with oxidative addition of C-Br, insertion, C-H activation, and reductive elimination in sequential steps.
Authors
- Shiuh‐Tzung Liu (ORCID: https://orcid.org/0000-0002-0544-006X)
- Yi‐Hung Liu (ORCID: https://orcid.org/0000-0003-3986-0086)
- C.-C. Hsu
Institutions
- National Taiwan University (TW)
Publication Details
- Journal
- The Journal of Organic Chemistry
- Published
- 2024-08-09
- DOI
- https://doi.org/10.1021/acs.joc.4c01286
- Citations
- 5
- Primary Topic
- Catalytic Alkyne Reactions
- Type
- article
- Field-Weighted Citation Impact
- 1.25
Funders
- National Science and Technology Council