Measuring repeatability of dynamic contrast-enhanced MRI biomarkers improves evaluation of biological response to radiotherapy in lung cancer
Few literature studies report quantitative imaging biomarker precision, by measuring repeatability or reproducibility. Several DCE-MRI biomarkers of lung cancer tumour microenvironment were highly repeatable. Repeatability coefficient measurements enabled lesion-specific evaluation of early biological response to therapy, improving conventional assessment.
Authors
- Ahmed Salem (ORCID: https://orcid.org/0000-0001-5148-7072)
- Corinne Faivre‐Finn (ORCID: https://orcid.org/0000-0001-5617-9781)
- Geoff J.M. Parker (ORCID: https://orcid.org/0000-0003-2934-2234)
- Nivetha Sridharan (ORCID: https://orcid.org/0000-0003-0956-9976)
- Susan Cheung (ORCID: https://orcid.org/0000-0003-1090-5762)
- Ross A. Little
- Maira Tariq (ORCID: https://orcid.org/0000-0002-2826-4046)
- Núria Porta (ORCID: https://orcid.org/0000-0003-2458-2167)
- Michael J. Dubec
- James P.B. O’Connor (ORCID: https://orcid.org/0000-0002-4044-8497)
Institutions
- Institute of Cancer Research (GB)
- Hashemite University (JO)
- University of Manchester (GB)
- Cancer Research UK Manchester Institute (GB)
- The Christie NHS Foundation Trust (GB)
- Absynth Biologics (United Kingdom) (GB)
- University College London (GB)
Publication Details
- Journal
- European Radiology
- Published
- 2024-08-09
- DOI
- https://doi.org/10.1007/s00330-024-10970-7
- Citations
- 5
- Primary Topic
- MRI in cancer diagnosis
- Type
- article
- Field-Weighted Citation Impact
- 2.02
Funders
- Royal Marsden NHS Foundation Trust
- Cancer Research UK
- National Institute for Health and Care Research