Impact of linked color imaging on the proximal adenoma miss rate: useful or not?

In this issue of Endoscopy, Karsenti et al. present an impressive randomized controlled trial investigating the impact of linked color imaging (LCI) on the proximal adenoma miss rate in a multicenter tandem setting [1]. The study examined whether LCI could detect more adenomas than white-light imaging (WLI) in the right-sided colon. The detection and resection of colorectal adenomas by colonoscopy is performed worldwide because it helps prevent colorectal cancer deaths. Routine colonoscopy is mainly performed under WLI. However, in a meta-analysis of 51 reports, the adenoma miss rate (AMR) of WLI was 26% (95%CI 23%–30%) [2].