Outcomes of First-Line Abiraterone Acetate or Enzalutamide for Older Adults With Metastatic Castration-Resistant Prostate Cancer According to Use of Upfront Docetaxel for Metastatic Castration-Sensitive Prostate Cancer in an International Multicenter
Despite the innate limitations of a retrospective design and relatively small size of the ADT+D cohort, this analysis suggests that elderly men receiving AA or Enza as first-line therapy for mCRPC have similar survival outcomes and tolerability, regardless of previous D for mCSPC.
Authors
- Alessandra Damassi (ORCID: https://orcid.org/0000-0001-5052-0870)
- Giuseppe Fotia (ORCID: https://orcid.org/0000-0002-2071-8971)
- Heather M. McClure (ORCID: https://orcid.org/0000-0002-4441-5609)
- Talal El Zarif (ORCID: https://orcid.org/0000-0002-4507-2396)
- Andrea Malgeri
- Edoardo Francini (ORCID: https://orcid.org/0000-0003-4270-7023)
- Praful Ravi (ORCID: https://orcid.org/0000-0002-7466-4702)
- Elisa Zanardi (ORCID: https://orcid.org/0000-0002-3252-4226)
- Daniel Yick Chin Heng
- Ricardo Pereira Mestre (ORCID: https://orcid.org/0000-0002-3123-3697)
- Gian Paolo Spinelli (ORCID: https://orcid.org/0000-0002-4363-6274)
- Richard M. Lee‐Ying (ORCID: https://orcid.org/0000-0003-0913-6046)
- Veronica Murianni (ORCID: https://orcid.org/0000-0002-4955-0295)
- Sabrina Rossetti (ORCID: https://orcid.org/0000-0002-9337-5885)
- Pier Vitale Nuzzo (ORCID: https://orcid.org/0000-0002-5618-8079)
- Antonio Russo (ORCID: https://orcid.org/0000-0002-4224-5343)
- Giuseppe Procopio (ORCID: https://orcid.org/0000-0002-2498-402X)
- Mikol Modesti (ORCID: https://orcid.org/0000-0003-1734-1461)
- Matthew P. Davidsohn (ORCID: https://orcid.org/0009-0000-1480-9423)
- Ugo De Giorgi (ORCID: https://orcid.org/0000-0001-7520-2908)
- Anna Patrikidou (ORCID: https://orcid.org/0000-0001-5066-601X)
- Thiago Martins Oliveira (ORCID: https://orcid.org/0009-0005-1690-5554)
- Calogero Saieva (ORCID: https://orcid.org/0000-0002-0117-1608)
- Charles Vauchier (ORCID: https://orcid.org/0000-0001-5340-2722)
- Sandro Pignata (ORCID: https://orcid.org/0000-0002-8836-2633)
- Loana Bueno Valença
- Daniele Santini (ORCID: https://orcid.org/0000-0002-9118-3337)
- Marc Eid (ORCID: https://orcid.org/0000-0002-4738-5695)
- Christopher Sweeney
Institutions
- Harvard University (US)
- Cornell University (US)
- Policlinico Umberto I (IT)
- Prevention Institute (US)
- Institut Gustave Roussy (FR)
- National Cancer Centre Japan (JP)
- Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IT)
- Institute of Oncology Research (CH)
- D’Or Institute for Research and Education (BR)
- Dana-Farber Cancer Institute (US)
- Centre for Cancer Biology (AU)
- Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale" (IT)
- Campus Bio Medico University Hospital (IT)
- Ospedale Policlinico San Martino (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- Fondazione IRCCS Istituto Nazionale dei Tumori (IT)
- Ospedali Riuniti Umberto I (IT)
- Weill Cornell Medicine (US)
- University of Florence (IT)
- The University of Adelaide (AU)
- Sapienza University of Rome (IT)
- University of Palermo (IT)
Publication Details
- Journal
- Clinical Genitourinary Cancer
- Published
- 2024-08-09
- DOI
- https://doi.org/10.1016/j.clgc.2024.102185
- Primary Topic
- Prostate Cancer Treatment and Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00