Associations between prenatal stress with offspring inflammation, depression and anxiety
Prenatal maternal stress is associated with IL-6 levels in childhood, and with GAD and depression during adolescence. Future studies should examine immune activity at multiple points during development in relation to mental health into adulthood to determine whether inflammation at different points during development could increase risk for mental health problems among children whose mothers experienced significant stressors during pregnancy.
Authors
- Zahra M. Clayborne (ORCID: https://orcid.org/0000-0003-2016-1015)
- Golam Mohammed Khandaker (ORCID: https://orcid.org/0000-0002-4935-9220)
- Stephen E. Gilman (ORCID: https://orcid.org/0000-0002-8331-6419)
- Ian Colman (ORCID: https://orcid.org/0000-0001-5924-0277)
Institutions
- Norwegian Institute of Public Health (NO)
- Johns Hopkins University (US)
- University of Ottawa (CA)
- University of Calgary (CA)
- University of Bristol (GB)
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (US)
Publication Details
- Journal
- Psychoneuroendocrinology
- Published
- 2024-08-09
- DOI
- https://doi.org/10.1016/j.psyneuen.2024.107162
- Citations
- 4
- Primary Topic
- Maternal Mental Health During Pregnancy and Postpartum
- Type
- article
- Field-Weighted Citation Impact
- 2.17
Funders
- Wellcome Trust
- University of Bristol
- Canada Research Chairs
- National Institutes of Health
- Medical Research Council
- National Institute of Child Health and Human Development
- Eunice Kennedy Shriver National Institute of Child Health and Human Development