Semiquantitative assessment of phosphatase and tensin homolog value with immunohistochemistry in colorectal cancer
Semiquantitative assessment with cell counting multiplied by color intensity is a good method in determining PTEN expression. The use of immunohistochemical staining intensity and cell scoring with ROC cut-off is effective to elaborate the effects of PTEN in colorectal cancer (PTEN value > 199.0 was classified as strong and ≤ 199.0 as weak).
Authors
- Asmarinah Asmarinah
- Trevino Aristarkus Pakasi (ORCID: https://orcid.org/0000-0003-0413-2011)
- Toar Jean Maurice Lalisang (ORCID: https://orcid.org/0000-0001-9734-080X)
- Sri Widia A. Jusman (ORCID: https://orcid.org/0000-0003-0471-5583)
- Aru Wisaksono Sudoyo (ORCID: https://orcid.org/0000-0002-4827-9392)
- Wifanto Saditya Jeo (ORCID: https://orcid.org/0000-0003-2194-1304)
- Nurjati Chairani Siregar
Institutions
- University of Indonesia (ID)
Publication Details
- Journal
- The International Journal of Biological Markers
- Published
- 2024-08-01
- DOI
- https://doi.org/10.1177/03936155241265346
- Primary Topic
- PI3K/AKT/mTOR signaling in cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00