Non-dialyzable uremic toxins and renal tubular cell damage in CKD patients: a systems biology approach
Notably, WNT1/11, AGT, FGF4/17/22, LMX1B, GATA4, and CXCL12 emerged as promising targets for further exploration in renal tubular pathology related to non-dialyzable uremic toxins. Understanding the molecular players and pathways linked to renal tubular dysfunction opens avenues for novel therapeutic interventions and improved clinical management of chronic kidney disease and its complications.
Authors
- Pejman Shadpour (ORCID: https://orcid.org/0000-0003-4171-4168)
- Akram Nakhaei (ORCID: https://orcid.org/0000-0003-0293-8206)
- Roya Asadi
Institutions
- University of Science and Culture (IR)
- Mazandaran University of Science and Technology (IR)
- Iran University of Medical Sciences (IR)
- Hasheminejad Kidney Center (IR)
Publication Details
- Journal
- European journal of medical research
- Published
- 2024-08-09
- DOI
- https://doi.org/10.1186/s40001-024-01951-z
- Citations
- 4
- Primary Topic
- Dialysis and Renal Disease Management
- Type
- article
- Field-Weighted Citation Impact
- 1.36