Decreased sirtuin 4 levels promote cellular proliferation and invasion in papillary thyroid carcinoma
This study provides novel insight into the potential contribution of SIRT4 to the regulation of the pathological progression of PTC. The data suggest that SIRT4 plays a tumor-suppressive role in PTC by inhibiting growth, survival, and invasive potential. Future research should investigate the molecular mechanisms underlying these effects of SIRT4.
Authors
- Ji‐Hyun Seo (ORCID: https://orcid.org/0000-0002-0691-3957)
- Somi Ryu (ORCID: https://orcid.org/0000-0002-6528-736X)
- Chae Dong Yim (ORCID: https://orcid.org/0000-0002-2110-1092)
- Young‐Sool Hah (ORCID: https://orcid.org/0000-0002-8571-2722)
- Jung Je Park (ORCID: https://orcid.org/0000-0001-6325-0398)
- Hyunjin Lee (ORCID: https://orcid.org/0000-0001-6585-0338)
- Seung Jun Lee (ORCID: https://orcid.org/0000-0002-3377-4833)
- So Young Cheon
- Seong Jun Won
Institutions
- Gyeongsang National University (KR)
- Gyeongsang National University Hospital (KR)
- Chung-Ang University (KR)
Publication Details
- Journal
- European Thyroid Journal
- Published
- 2024-08-09
- DOI
- https://doi.org/10.1530/etj-24-0079
- Citations
- 1
- Primary Topic
- Sirtuins and Resveratrol in Medicine
- Type
- article
- Field-Weighted Citation Impact
- 0.34
Funders
- National Research Foundation
- Gyeongsang National University
- National Research Foundation of Korea