Brain mGlu5 Is Linked to Cognition and Cigarette Smoking but Does Not Differ From Control in Early Abstinence From Chronic Methamphetamine Use
Abstinent MUD patients show no evidence of mGlu5 downregulation in brain, but association of VT in dorsolateral prefrontal cortex with verbal learning suggests that medications that target mGlu5 may improve cognitive performance.
Authors
- Andy C. Dean
- Judah Farahi
- Edythe D. London (ORCID: https://orcid.org/0000-0003-3577-7808)
- Dara G. Ghahremani (ORCID: https://orcid.org/0000-0001-6731-6817)
- M. Mandelkern (ORCID: https://orcid.org/0000-0002-1189-2775)
- Jean‐Baptiste Pochon (ORCID: https://orcid.org/0000-0002-0629-7779)
- Daicia C. Allen (ORCID: https://orcid.org/0000-0002-4767-1237)
- Larissa J. Mooney (ORCID: https://orcid.org/0000-0003-1556-731X)
- Tarannom Mahmoudie
- Megan N. McClintick (ORCID: https://orcid.org/0000-0003-3399-733X)
- Edwin Partiai
- Robert A Casillas
- Hilary Lachoff
- Robert Kessler
Institutions
- University of California, Los Angeles (US)
- University of California, Irvine (US)
- VA Greater Los Angeles Healthcare System (US)
Publication Details
- Journal
- The International Journal of Neuropsychopharmacology
- Published
- 2024-08-01
- DOI
- https://doi.org/10.1093/ijnp/pyae031
- Citations
- 2
- Primary Topic
- Neurotransmitter Receptor Influence on Behavior
- Type
- article
- Field-Weighted Citation Impact
- 0.54
Funders
- National Institutes of Health