Prognostic significance of invasive cribriform gland size and percentage in Gleason score 7 prostate adenocarcinoma
Our findings suggest that the presence of a cribriform pattern, increases in the percentage of such patterns, and increases in the size of the largest cribriform gland within a given tumor are associated with poor prognosis. We suggest that a more aggressive clinical approach may be needed in Grade Group 2 and 3 cases with invasive cribriform glands larger than 0.5 mm and a cribriform gland percentage greater than 10%, especially in prostate needle biopsy specimens.
Authors
- Ata Özen (ORCID: https://orcid.org/0000-0002-0890-486X)
- Cavit Can (ORCID: https://orcid.org/0000-0003-2267-2759)
- Ertuğrul Çolak (ORCID: https://orcid.org/0000-0003-3251-1043)
- Nazlı Sena Şeker (ORCID: https://orcid.org/0000-0003-4588-7250)
- Emel Tekin (ORCID: https://orcid.org/0000-0001-7297-9869)
- Mustafa Fuat Açıkalın (ORCID: https://orcid.org/0000-0003-1708-467X)
Institutions
- Eskişehir Osmangazi University (TR)
Publication Details
- Journal
- American Journal of Clinical Pathology
- Published
- 2024-08-09
- DOI
- https://doi.org/10.1093/ajcp/aqae082
- Citations
- 2
- Primary Topic
- Prostate Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.84