Predicting early-stage coronary artery disease using machine learning and routine clinical biomarkers improved by augmented virtual data
Accurate predictions of angiographic CAD can be obtained using a set of routine laboratory markers, age, sex, and smoking status, holding the potential to limit the need for invasive diagnostic techniques. The extension analysis in the YFS demonstrated the potential of these findings in a younger population, and it confirmed applicability to atherosclerotic vascular disease.
Authors
- Winfried März (ORCID: https://orcid.org/0000-0001-6083-8946)
- Jos A. Bosch (ORCID: https://orcid.org/0000-0001-7780-4806)
- Costas Papaloukas (ORCID: https://orcid.org/0000-0002-6736-5536)
- Dimitrios I. Fotiadis (ORCID: https://orcid.org/0000-0002-5987-9350)
- Pashupati P. Mishra (ORCID: https://orcid.org/0000-0001-5177-3431)
- Olli T. Raitakari (ORCID: https://orcid.org/0000-0001-9365-3702)
- Rick Quax (ORCID: https://orcid.org/0000-0002-0299-0074)
- Antonis I. Sakellarios (ORCID: https://orcid.org/0000-0002-2272-9543)
- Terho J. Lehtimäki (ORCID: https://orcid.org/0000-0002-2555-4427)
- Vasileios S. Loukas (ORCID: https://orcid.org/0000-0001-6390-884X)
- Cillian Hourican (ORCID: https://orcid.org/0009-0002-3161-0736)
- Angela Koloi (ORCID: https://orcid.org/0009-0001-8197-3749)
Institutions
- University of Turku (FI)
- Tampere University (FI)
- University of Patras (GR)
- University of Mannheim (DE)
- University of Ioannina (GR)
- Medical University of Graz (AT)
- Heidelberg University (DE)
- Turku University Hospital (FI)
- FORTH Institute of Molecular Biology and Biotechnology (GR)
- Synlab (Germany) (DE)
- Fimlab (Finland) (FI)
- University of Amsterdam (NL)
Publication Details
- Journal
- European Heart Journal - Digital Health
- Published
- 2024-08-09
- DOI
- https://doi.org/10.1093/ehjdh/ztae049
- Citations
- 16
- Primary Topic
- Cardiac Imaging and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 6.47
Funders
- Foundation for Cardiovascular Research
- Yrjö Jahnssonin Säätiö
- European Commission
- Kela
- Suomen Kulttuurirahasto
- Juho Vainion Säätiö
- Signe ja Ane Gyllenbergin Säätiö
- Emil Aaltosen Säätiö
- Sydäntutkimussäätiö
- Tampereen Tuberkuloosisäätiö
- Diabetesliitto
- Paavo Nurmen Säätiö
- Tays
- Syöpäsäätiö