Efficacy and safety of novel freeze‐dried plasma products in a porcine combat casualty model
Both CLP and PCLP exhibit promising therapeutic potential for managing hemorrhagic shock in scenario where whole blood supplies are limited. However, the distinct physiological and coagulation characteristics of the swine model necessitate further investigation using humanized preclinical models to fully understand their clinical applicability and constraints.
Authors
- Nicolas Prat
- Philippe Vest (ORCID: https://orcid.org/0009-0003-7878-7667)
- Florent Montespan (ORCID: https://orcid.org/0000-0003-4905-9962)
- Frédérique Dufour‐Gaume (ORCID: https://orcid.org/0009-0008-0632-0247)
- Nadira Frescaline (ORCID: https://orcid.org/0000-0002-2673-8025)
- Vénétia Cardona (ORCID: https://orcid.org/0000-0002-7598-680X)
- Anne‐Margaux Legland ép. Dejean (ORCID: https://orcid.org/0000-0001-5852-9829)
- Audrey Bordone
Institutions
- Hôpital d'instruction des Armées Percy (FR)
Publication Details
- Journal
- Transfusion
- Published
- 2024-08-09
- DOI
- https://doi.org/10.1111/trf.17971
- Citations
- 3
- Primary Topic
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Type
- article
- Field-Weighted Citation Impact
- 1.27
Funders
- Georgia Clinical and Translational Science Alliance