O uso de metronidazol em feridas neoplásicas malignas de pacientes sob cuidados paliativos em uma instituição pública no Distrito Federal, Brasil

Palliative care (PC) is essential for oncology patients, especially those with malignant neoplastic wounds (MNW) that produce unpleasant odor, causing impacts such as vomiting and social isolation. Metronidazole is often used off-label to treat this symptom. This descriptive, cross-sectional study investigated the profile of patients who received metronidazole for odor control in MNW and evaluated the benefits of this treatment. Conducted from January 2018 to December 2022 at a CP reference hospital in the Federal District, with patients admitted to the oncology ward for palliative care, retrospective chart analysis revealed that 87.04% of patients benefited from the medication. Head and neck cancer was the predominant diagnosis among the 30 patients included, 17 of whorm were men (56.67%). The study demonstrates consistent improvements in odor control in MNW with the use of metronidazole, reinforcing its efficacy in this specific clinical context.

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Publication Details

Journal
Espaço para a Saúde - Revista de Saúde Pública do Paraná
Published
2024-08-09
DOI
https://doi.org/10.22421/1517-7130/es.2024v25.e1009
Primary Topic
Oral health in cancer treatment
Type
article
Field-Weighted Citation Impact
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article

O uso de metronidazol em feridas neoplásicas malignas de pacientes sob cuidados paliativos em uma instituição pública no Distrito Federal, Brasil

Débora Ferreira Reis, Emília Vitória da Silva, Daniel S. Guedes, Alliny do Nascimento Martins et al.
Espaço para a Saúde - Revista de Saúde Pública do Paraná
Oral health in cancer treatment
article

O uso de metronidazol em feridas neoplásicas malignas de pacientes sob cuidados paliativos em uma instituição pública no Distrito Federal, Brasil

Débora Ferreira Reis, Emília Vitória da Silva, Daniel S. Guedes, Alliny do Nascimento Martins, Laís Manuela Borges Ribeiro
article en

Abstract

Palliative care (PC) is essential for oncology patients, especially those with malignant neoplastic wounds (MNW) that produce unpleasant odor, causing impacts such as vomiting and social isolation. Metronidazole is often used off-label to treat this symptom. This descriptive, cross-sectional study investigated the profile of patients who received metronidazole for odor control in MNW and evaluated the benefits of this treatment. Conducted from January 2018 to December 2022 at a CP reference hospital in the Federal District, with patients admitted to the oncology ward for palliative care, retrospective chart analysis revealed that 87.04% of patients benefited from the medication. Head and neck cancer was the predominant diagnosis among the 30 patients included, 17 of whorm were men (56.67%). The study demonstrates consistent improvements in odor control in MNW with the use of metronidazole, reinforcing its efficacy in this specific clinical context.

Espaço para a Saúde - Revista de Saúde Pública do ParanáVol. 25
Defence Research and Development Organisation (IN), Universidade de Brasília (BR), Governo do Distrito Federal (BR), Secretaria de Estado de Educação do Distrito Federal (BR), Contextual Change (United States) (US), Sociedad Española de Cuidados Intensivos Pediátricos (ES), Departamento de Ciência e Tecnologia (BR)
Good health and well-being
Openalex Percentile: Top 76%
Oral health in cancer treatment
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O uso de metronidazol em feridas neoplásicas malignas de pacientes sob cuidados paliativos em uma instituição pública no Distrito Federal, Brasil — Débora Ferreira Reis, Emília Vitória da Silva, et al. · Espaço para a Saúde - Revista de Saúde Pública do Paraná (2024) | TGRS Research Map | TGRS