Tobacco smoking is associated with sex- and plaque-type specific upregulation of CRLF1 in atherosclerotic lesions
Atherosclerotic plaques from current smokers show sex-dependent upregulation of smooth muscle cell gene CRLF1. This may explain the different contributions of smoking to cardiovascular risk in females.
Authors
- Lü Tian (ORCID: https://orcid.org/0000-0002-5893-0169)
- Mete Civelek (ORCID: https://orcid.org/0000-0002-8141-0284)
- Ernest Diez Benavente (ORCID: https://orcid.org/0000-0002-4313-4290)
- Dominique P.V. de Kleijn (ORCID: https://orcid.org/0000-0003-2714-2140)
- Hester M. den Ruijter (ORCID: https://orcid.org/0000-0001-9762-014X)
- Michal Mokrý (ORCID: https://orcid.org/0000-0002-5298-4852)
- Gerard Pasterkamp
- Luka Hoeben
- R Noah Perry
- Kaylin Palm
Institutions
- Utrecht University (NL)
- University Medical Center Utrecht (NL)
- University of Virginia (US)
Publication Details
- Journal
- Atherosclerosis
- Published
- 2024-08-08
- DOI
- https://doi.org/10.1016/j.atherosclerosis.2024.118554
- Citations
- 9
- Primary Topic
- Cardiovascular Disease and Adiposity
- Type
- article
- Field-Weighted Citation Impact
- 3.62
Funders
- Heart Foundation
- Expect Miracles Foundation
- Fondation Leducq
- Hartstichting
- Universitair Medisch Centrum Utrecht
- China Scholarship Council
- Horizon 2020 Framework Programme
- H2020 Society