Liver Extracellular Vesicles and Particles Enriched β-Sitosterol Effectively Promote Liver Regeneration in Mice
Liver-derived EVPs promote regeneration after partial hepatectomy. β-sitosterol from EVPs accelerates fatty acid oxidation and promotes liver regeneration by activating Hedgehog signaling pathway.
Authors
- Minghe Zhang
- Xiangdong Gongye (ORCID: https://orcid.org/0009-0001-1267-1835)
- Chengming Qu (ORCID: https://orcid.org/0000-0002-9773-8815)
- Yufeng Yuan (ORCID: https://orcid.org/0000-0001-7472-4368)
- Zhang Chen (ORCID: https://orcid.org/0000-0002-6072-8226)
- Peng Xia (ORCID: https://orcid.org/0000-0002-6046-3790)
- Ming Tian (ORCID: https://orcid.org/0000-0003-4014-7392)
- Yingyi Liu (ORCID: https://orcid.org/0000-0002-7745-8445)
- Yibo Chai
- Tianyin Ma
- Jie Liu (ORCID: https://orcid.org/0000-0003-4868-6972)
- Yimin Zhu (ORCID: https://orcid.org/0000-0002-8122-0958)
- Wing Wa Guo
Institutions
- Wuhan University (CN)
- Zhongnan Hospital of Wuhan University (CN)
Publication Details
- Journal
- International Journal of Nanomedicine
- Published
- 2024-08-01
- DOI
- https://doi.org/10.2147/ijn.s465346
- Citations
- 2
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 0.47
Funders
- Health Commission of Hubei Province
- China Postdoctoral Science Foundation
- Wuhan University
- Zhongnan Hospital of Wuhan University
- National Postdoctoral Program for Innovative Talents
- Fundamental Research Funds for the Central Universities