Topically applied, fatty acid‐containing formulations provide superior barrier benefits in an ex vivo tape‐stripped skin model
These findings demonstrate that FFA-containing formulations can repair damaged ex vivo skin and point to a repair mechanism in which topically applied palmitic and stearic acids, (which boost lipid levels and elongation) can increase the production and transport of lipids into a repaired SC and thus rebuild an effective skin barrier.
Authors
- Ana Villa (ORCID: https://orcid.org/0000-0002-4025-9506)
- Stella Arcella
- Dawn Mihalov (ORCID: https://orcid.org/0000-0001-9408-0643)
- John Bajor (ORCID: https://orcid.org/0000-0003-4614-6956)
- Andrew E. Mayes (ORCID: https://orcid.org/0000-0003-4060-0660)
- Hilal Ilarslan (ORCID: https://orcid.org/0009-0006-4859-7741)
- Samantha Samaras
- Manoj Misra (ORCID: https://orcid.org/0000-0001-7895-8882)
- John Nip (ORCID: https://orcid.org/0009-0005-7781-4736)
- Lin Feng (ORCID: https://orcid.org/0000-0001-9124-1544)
Institutions
- Unilever (United Kingdom) (GB)
- Unilever (United States) (US)
- Data Power Decisions (United States) (US)
Publication Details
- Journal
- International Journal of Cosmetic Science
- Published
- 2024-08-01
- DOI
- https://doi.org/10.1111/ics.12961
- Citations
- 5
- Primary Topic
- Advancements in Transdermal Drug Delivery
- Type
- article
- Field-Weighted Citation Impact
- 1.04
Funders
- Unilever