Characterization of Inflammation/Immune‐, Acute Phase‐, Extracellular Matrix‐, Adhesion‐, and Serine Protease‐Related Proteins in the Amniotic Fluid of Women With Early Preterm Prelabor Rupture of Membranes
ECM (lumican, SPRAC, TGFBI, and TGF-β1)- and serine protease (uPA)-associated proteins in the AF are involved in the regulation of the host response to infection/inflammation in the amniotic cavity, whereas AF inflammation (IL-8, MMP-8, and IL-6)-associated mediators are implicated in the development of preterm parturition and major NMM in early PPROM.
Authors
- Kyong‐No Lee (ORCID: https://orcid.org/0000-0002-8796-0498)
- Bo Young Choi (ORCID: https://orcid.org/0000-0002-9579-3503)
- Iseop Cho
- Kyo Hoon Park (ORCID: https://orcid.org/0000-0003-3550-9686)
- Ji Eun Kim (ORCID: https://orcid.org/0000-0003-3094-2229)
- Min Jung Lee (ORCID: https://orcid.org/0000-0001-8293-3418)
Institutions
- Seoul National University Bundang Hospital (KR)
- Chungnam National University Hospital (KR)
Publication Details
- Journal
- American Journal of Reproductive Immunology
- Published
- 2024-08-01
- DOI
- https://doi.org/10.1111/aji.13913
- Citations
- 4
- Primary Topic
- Preterm Birth and Chorioamnionitis
- Type
- article
- Field-Weighted Citation Impact
- 1.55