Production Methods and Biomedical Applications of Materials Based on Poly-3-hydroxybutyrate and Its Compositions

Abstract—The review presents publications devoted to a promising biopolymer, poly-3-hydroxybutyrate, and composite materials based on it. The structure and properties of the materials are considered. The main focus is on the biomedical application of these biopolymer materials. The main advantage of poly-3-hydroxybutyrate is its biodegradability in nature and living systems, biocompatibility, hemocompatibility, and thromboresistance. This biopolymer also possesses processability. The products and materials based on it can be processed by solution and melt production methods. The review pays great attention to the production of ultrathin fibers by electrospinning. Materials based on poly-3-hydroxybutyrate even now find wide application in medicine, hygiene, packaging, and ecology.