Clinical diagnostic value of metagenomic next-generation sequencing in patients with acute infection in emergency department
Compared to culture methods, mNGS demonstrates superior positive rates, sensitivity, and accuracy in the rapid detection of acute infections, particularly in critically ill patients such as those with sepsis. This capability establishes a foundation for the swift and precise identification of pathogens, allowing for the analysis of clinical indicators and patient prognosis based on the extensive data generated from mNGS.
Authors
- Weiwei Wu (ORCID: https://orcid.org/0000-0002-9020-1302)
- Lingyu Wei (ORCID: https://orcid.org/0000-0002-9947-4569)
- Jieyu Luo
- Jia Xu (ORCID: https://orcid.org/0000-0002-0342-0137)
- Xue Xu (ORCID: https://orcid.org/0000-0001-6045-3712)
- Jia Yin
- Zaiyuan Sun
- Wenqian Gong
Institutions
- Sun Yat-sen University (CN)
- The Seventh Affiliated Hospital of Sun Yat-sen University (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
Publication Details
- Journal
- Heliyon
- Published
- 2024-08-01
- DOI
- https://doi.org/10.1016/j.heliyon.2024.e35802
- Citations
- 4
- Primary Topic
- Bacterial Identification and Susceptibility Testing
- Type
- article
- Field-Weighted Citation Impact
- 1.52
Funders
- National Natural Science Foundation of China