Exosomal circ‐0100519 promotes breast cancer progression via inducing M2 macrophage polarisation by USP7/NRF2 axis
Our study revealed that exosomal circ-0100519 is a potential biomarker for BC diagnosis and prognosis, and the HIF-1α inhibitor PX-478 may provide a therapeutic target for BC.
Authors
- Xiaoan Liu (ORCID: https://orcid.org/0000-0001-5716-0740)
- Minyu Zhuang (ORCID: https://orcid.org/0009-0009-7226-2169)
- Li Shen (ORCID: https://orcid.org/0000-0002-8813-5449)
- Jie Ji (ORCID: https://orcid.org/0000-0001-7071-9780)
- Xiaoqiang Zhang (ORCID: https://orcid.org/0000-0002-8172-6684)
- Hongfei Zhang (ORCID: https://orcid.org/0000-0001-7558-4934)
- Yanhui Zhu (ORCID: https://orcid.org/0000-0001-8475-1271)
Institutions
- Zhejiang Cancer Hospital (CN)
- Second Affiliated Hospital of Nanjing Medical University (CN)
- Jiangsu Province Hospital (CN)
- Second Affiliated Hospital of Zhejiang University (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Clinical and Translational Medicine
- Published
- 2024-08-01
- DOI
- https://doi.org/10.1002/ctm2.1763
- Citations
- 33
- Primary Topic
- Circular RNAs in diseases
- Type
- article
- Field-Weighted Citation Impact
- 7.72
Funders
- National Natural Science Foundation of China