A Rare Case of Primary Squamous Cell Carcinoma of the Stomach: A Case Report

Pure primary gastric squamous cell carcinoma (PGSCC) is a notably rare gastric malignancy. We present the case of a 51-year-old woman with advanced gastric squamous cell carcinoma characterized by a 7.6 cm necrotic mass invading the proximal stomach, liver metastasis, and lymphadenopathy at diagnosis. Despite the lack of standardized treatment protocols, we review tumor markers and potential management strategies, including surgical and chemotherapeutic interventions. The rarity and aggressive nature of PGSCC necessitates further research to develop effective detection and treatment methods to improve patient prognosis and survival outcomes.

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Publication Details

Journal
Cureus
Published
2024-08-05
DOI
https://doi.org/10.7759/cureus.66220
Primary Topic
Colorectal and Anal Carcinomas
Type
article
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0.00
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article

A Rare Case of Primary Squamous Cell Carcinoma of the Stomach: A Case Report

Gautam Maddineni, Edward Jurkovic, Julia Janecki, Abby Kunitsky et al.
Cureus
Colorectal and Anal Carcinomas
article

A Rare Case of Primary Squamous Cell Carcinoma of the Stomach: A Case Report

Gautam Maddineni, Edward Jurkovic, Julia Janecki, Abby Kunitsky, Vladimir Ferrer
article en

Abstract

Pure primary gastric squamous cell carcinoma (PGSCC) is a notably rare gastric malignancy. We present the case of a 51-year-old woman with advanced gastric squamous cell carcinoma characterized by a 7.6 cm necrotic mass invading the proximal stomach, liver metastasis, and lymphadenopathy at diagnosis. Despite the lack of standardized treatment protocols, we review tumor markers and potential management strategies, including surgical and chemotherapeutic interventions. The rarity and aggressive nature of PGSCC necessitates further research to develop effective detection and treatment methods to improve patient prognosis and survival outcomes.

CureusVol. 16(8)
Florida State University (US), Kansas City University (US), The University of Kansas Health System (US), McLaren Macomb (US), Lee Memorial Health System (US)
Zero hunger
Openalex Percentile: Top 76%
Colorectal and Anal Carcinomas
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