Proceedings of the 15 <sup>th</sup> International Newborn Brain Conference: Other forms of brain monitoring, such as NIRS, fMRI, biochemical, etc.
BACKGROUND AND OBJECTIVE: Preterm neonates with intraventricular hemorrhage (IVH) are at risk for posthemorrhagic ventricular dilatation (PHVD).In recent years targeted proteomics has developed into a powerful protein quantifi cation tool in biomedical research, systems biology, and clinical applications.This study aims to inform therapeutic decision-making and parental counseling using proteomics in this high-risk group. METHODS:In this prospective study, we investigated preterm neonates born <34 weeks of gestation between 2011 to 2023 with intraventricular hemorrhage (IVH).We performed targeted proteomics analysis on different biological matrices (blood, urine, and CSF), derived from a longitudinal neonatal cohort spanning a decade.We employed explainable machine learning (ML) algorithms
Authors
- Christina H. Wolfsberger (ORCID: https://orcid.org/0000-0002-9770-3487)
- Julia Tatz
- Aisling A. Garvey (ORCID: https://orcid.org/0000-0002-8443-3246)
- Gianluca Lista (ORCID: https://orcid.org/0000-0002-6636-5673)
- Monika Olischar (ORCID: https://orcid.org/0000-0001-6000-2137)
- Julia Buchmayer (ORCID: https://orcid.org/0000-0001-5473-4155)
- Sara Cherkerzian
- Christoph Schlatzer (ORCID: https://orcid.org/0009-0007-5817-4117)
- Emanuele Bartolini (ORCID: https://orcid.org/0000-0002-5683-1941)
- Gerhard Pichler
- Katharina Goeral (ORCID: https://orcid.org/0000-0002-5209-6169)
- Christoph E. Schwarz (ORCID: https://orcid.org/0000-0003-0975-1575)
- Rathinaswamy B. Govindan (ORCID: https://orcid.org/0000-0001-9149-332X)
- Nariae Baik‐Schneditz (ORCID: https://orcid.org/0000-0003-1879-6652)
- Steven J. Schiff (ORCID: https://orcid.org/0000-0003-2623-3614)
- Ronald Mulondo
- Eugene Dempsey (ORCID: https://orcid.org/0000-0002-6266-3462)
- Marvin Seruwu (ORCID: https://orcid.org/0000-0002-2737-8762)
- Deirdre M. Murray (ORCID: https://orcid.org/0000-0002-2201-9912)
- Georg Marcus Schmölzer (ORCID: https://orcid.org/0000-0001-9798-2415)
- Marlies Bruckner (ORCID: https://orcid.org/0000-0003-3429-7597)
- Nicholas Nicoletti
- Tatiana Nuzum
- Chelsea Munster (ORCID: https://orcid.org/0000-0003-4635-7390)
- Oğuz Tuncer (ORCID: https://orcid.org/0000-0003-3706-414X)
- Berndt Urlesberger (ORCID: https://orcid.org/0000-0003-0648-5785)
- Khorshid Mohammad (ORCID: https://orcid.org/0000-0002-3568-7282)
- Pauline de Jesus
- Silvia Schönthaler
- Moses Wabukoma
- Jenny Bua (ORCID: https://orcid.org/0000-0003-2599-0701)
- Eyyüp Yürektürk (ORCID: https://orcid.org/0000-0001-7867-0184)
- Edith Mbabazi Kabachelor
- John B. Sunwoo (ORCID: https://orcid.org/0000-0002-8393-4196)
- Andrea Pardo (ORCID: https://orcid.org/0009-0000-5255-7976)
- Helen Christou (ORCID: https://orcid.org/0000-0002-3104-4570)
- Maria Angela Franceschini (ORCID: https://orcid.org/0000-0001-6758-423X)
- Joshua Magombe (ORCID: https://orcid.org/0000-0002-5017-0206)
- Balázs Hauser (ORCID: https://orcid.org/0000-0001-9254-2189)
- Sean Mathieson (ORCID: https://orcid.org/0000-0001-6498-6620)
- Elena V. Wachtel (ORCID: https://orcid.org/0000-0002-1172-0244)
- Lilijana Kornhauser-Cerar
- Jason Sutin (ORCID: https://orcid.org/0000-0002-9492-3978)
- Anna Lucia Paltrinieri (ORCID: https://orcid.org/0000-0002-4560-6917)
- Mohamed El‐Dib (ORCID: https://orcid.org/0000-0001-6979-7407)
- Andreea Pavel (ORCID: https://orcid.org/0000-0002-7233-3408)
- Kerstin Gründler
- Rutvi Vyas (ORCID: https://orcid.org/0000-0001-7177-0721)
- Laila Springer (ORCID: https://orcid.org/0000-0001-6284-9673)
- Dimitrios Rallis (ORCID: https://orcid.org/0000-0002-5156-0345)
- Gregor J. Kasprian (ORCID: https://orcid.org/0000-0003-3858-3347)
- Hoda El-Shibiny (ORCID: https://orcid.org/0000-0002-5662-1661)
- Enikő Szakmár (ORCID: https://orcid.org/0000-0002-8848-8092)
- Miklós Szabó (ORCID: https://orcid.org/0000-0003-3317-5619)
- Brenda Hiu Yan Law (ORCID: https://orcid.org/0000-0002-4819-9253)
- Ajay Rajaram (ORCID: https://orcid.org/0000-0002-0949-4137)
- Kristine Woodward (ORCID: https://orcid.org/0000-0002-2368-0454)
- James P. Boardman (ORCID: https://orcid.org/0000-0003-3904-8960)
- Michael Woglom
- Katrin Klebermass‐Schrehof (ORCID: https://orcid.org/0000-0001-5387-6602)
- Sean M. Bailey
- Georg Langs
- Nur Aycan
- Ceyda Acun (ORCID: https://orcid.org/0000-0002-9924-1343)
- Subhash Puthuraya (ORCID: https://orcid.org/0000-0001-9616-9115)
- Mirjam Steiner (ORCID: https://orcid.org/0009-0009-5681-981X)
- Vito Giordano (ORCID: https://orcid.org/0000-0002-2094-8523)
- Bernhard Schwaberger (ORCID: https://orcid.org/0000-0001-5499-3712)
- Klemens Vierlinger (ORCID: https://orcid.org/0000-0001-6038-5895)
- P. Ellen Grant (ORCID: https://orcid.org/0000-0003-1005-4013)
- Esther Nalule
- C. Hsiao (ORCID: https://orcid.org/0000-0002-5211-3002)
- Terrie E. Inder (ORCID: https://orcid.org/0000-0002-6012-9944)
- Silvia Orlandi (ORCID: https://orcid.org/0000-0003-2733-8450)
- Hans Friedrich Fuchs (ORCID: https://orcid.org/0000-0003-4764-8050)
- Daniel Pfurtscheller (ORCID: https://orcid.org/0000-0001-8632-2905)
- U Kiechl-Kohlendorfer
- M. O'Donnell
- Seh Hyun Kim (ORCID: https://orcid.org/0000-0001-8686-1909)
- Hany Aly (ORCID: https://orcid.org/0000-0001-7395-6394)
- Daragh Finn
- Vicki Livingstone (ORCID: https://orcid.org/0000-0002-3309-1231)
- Davis Natukwatsa (ORCID: https://orcid.org/0000-0002-3182-9327)
- Geraldine B. Boylan
- Ágnes Jermendy (ORCID: https://orcid.org/0000-0002-2211-7272)
- Martha Caprio (ORCID: https://orcid.org/0000-0002-9459-0720)
- Ilaria Stucchi
- Murat Başaranoğlu (ORCID: https://orcid.org/0000-0003-4408-7075)
- Janine Y. Khan
- Tomasz Szczapa (ORCID: https://orcid.org/0000-0002-5214-2719)
- Angelika Berger (ORCID: https://orcid.org/0000-0001-8775-2405)
- Sarah D. Schlatterer (ORCID: https://orcid.org/0000-0002-6735-5776)
- Sandra Pusil (ORCID: https://orcid.org/0000-0002-8395-1113)
- Tina Perme (ORCID: https://orcid.org/0000-0002-6629-2531)
- Katie Hannon
- Àngel Bazán (ORCID: https://orcid.org/0009-0008-7588-7220)
- Lukas Mileder
- Sarolta H. Trinh
- Luca Laura Bogner
- Wei Liu (ORCID: https://orcid.org/0000-0002-2187-8125)
- Serap Karaman
- Pei‐Yi Lin (ORCID: https://orcid.org/0000-0003-3685-3331)
- Michael Moore (ORCID: https://orcid.org/0000-0003-2748-9988)
- John E. OʼToole (ORCID: https://orcid.org/0000-0002-7802-4948)
- Seth R. Goldstein
- Alam Randhawa
- Priska Bauerstätter (ORCID: https://orcid.org/0000-0001-9850-7181)
- Starlin Tindimwebwa
- Gabriel A. Vignolle
- Collins Akugizibwe
- Venkata Chirumammilla
- Isaac Emurang
- German Figueroa
- Imran Ilahi
- Enock Kainja
- Miriah Kemigisha Katugi
- Melinda Kis-Tamás
- Rakesh Lavu
- Cara Pleau
- Ana Laguna Pradas
- Helen L Turner (ORCID: https://orcid.org/0000-0003-0095-9759)
- Magdolna Barra
- Julia Elis
- Sreenivas Karnati
- Berenice Ramirez
- Łukasz Karpiński
- Simeo Ochieng
- Lisa Klein
- Christa Nöhammer
- Marlene Hammer
- Nicola J. Robertson
- Derya Cay Demir (ORCID: https://orcid.org/0009-0006-9922-2325)
- Vera Balog
- Alexa AschAlexander Avian
- Benjamin C. Warf (ORCID: https://orcid.org/0000-0001-6376-4751)
- Michael J. Esser
Institutions
- Semmelweis University (HU)
- Brigham and Women's Hospital (US)
- Boston Children's Hospital (US)
- Children's Hospital of Orange County (US)
- AIT Austrian Institute of Technology GmbH (AT)
- Harvard University (US)
- Innsbruck Medical University (AT)
- Universität Innsbruck (AT)
- University of Ioannina (GR)
- Medical University of Graz (AT)
- University of California, Irvine (US)
- University College Cork (IE)
- Ljubljana University Medical Centre (SI)
- Cork University Hospital (IE)
- Yale University (US)
- Massachusetts General Hospital (US)
- Comprehensive Cancer Center Vienna (AT)
- Laboratori Guglielmo Marconi (Italy) (IT)
- Infant (IE)
- University Children's Hospital Tübingen (DE)
- Athinoula A. Martinos Center for Biomedical Imaging (US)
- Ospedale dei Bambini Vittore Buzzi (IT)
- Boston Children's Museum (US)
- CURE Children’s Hospital of Uganda (UG)
- Universitat de Barcelona (ES)
- Medical University of Vienna (AT)
- University of Bologna (IT)
Publication Details
- Journal
- Journal of Neonatal-Perinatal Medicine
- Published
- 2024-08-05
- DOI
- https://doi.org/10.3233/npm-249004
- Primary Topic
- Neonatal and fetal brain pathology
- Type
- article
- Field-Weighted Citation Impact
- 0.00