Exercise-augmented THSD7B exhibited a positive prognostic implication and tumor-suppressed functionality in pan-cancer
This study underscores the dual role of exercise in modulating gene expression relevant to tumor growth and highlights the potential of THSD7B as a therapeutic target in cancer. Future research should further explore the specific mechanisms by which exercise and THSD7B influence cancer progression and develop immunotherapy-enhanced strategies to change patient outcomes in clinical settings.
Authors
- Qizhi Liu
- Yanwei He (ORCID: https://orcid.org/0000-0003-3377-6246)
- Zhiwen Luo (ORCID: https://orcid.org/0000-0002-0524-9951)
- Shuo Chen (ORCID: https://orcid.org/0000-0002-5122-3656)
- Jinguo Zhu (ORCID: https://orcid.org/0000-0001-9118-5335)
- Yisheng Chen (ORCID: https://orcid.org/0000-0001-6498-7519)
- Shiyi Chen (ORCID: https://orcid.org/0000-0001-9190-3122)
- Qin Wang (ORCID: https://orcid.org/0000-0002-4955-1490)
- Renwen Wan
- Rui Xu (ORCID: https://orcid.org/0000-0001-5116-4193)
- Zhengyuan Fang
Institutions
- Nanjing University of Chinese Medicine (CN)
- Dalian Medical University (CN)
- Fudan University (CN)
- Shanghai University of Traditional Chinese Medicine (CN)
- Traditional Chinese Medicine Hospital of Kunshan (CN)
- First Affiliated Hospital of Dalian Medical University (CN)
- Huashan Hospital (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2024-08-05
- DOI
- https://doi.org/10.3389/fimmu.2024.1440226
- Citations
- 10
- Primary Topic
- PARP inhibition in cancer therapy
- Type
- article
- Field-Weighted Citation Impact
- 2.83
Funders
- National Natural Science Foundation of China