Urinary excretion of gluten immunoreactive peptides as an indicator of gastrointestinal function after fasting and dietary provocation in healthy volunteers
This study sheds light on the temporal dynamics of u-GIP in comparison to lactulose and mannitol, established probes for assessing intestinal permeability. The resemblance between u-GIP and lactulose excretion patterns aligns with the anticipated paracellular permeability pathway. The capacity to detect antigenic food protein fragments in urine opens novel avenues for studying protein metabolism and monitoring pathologies related to the digestive and intestinal systems.
Authors
- Irati Mendía (ORCID: https://orcid.org/0000-0001-9584-7885)
- Joshua C. D. Long (ORCID: https://orcid.org/0000-0002-6476-2026)
- M.A. Fernández-Peralbo (ORCID: https://orcid.org/0000-0002-2767-2750)
- Ángel Cebolla (ORCID: https://orcid.org/0000-0002-6976-4522)
- Raquel Rodríguez-Ramírez
- Carolina Sousa (ORCID: https://orcid.org/0000-0002-9235-9496)
Institutions
- Universidad de Granada (ES)
- Biomedal (Spain) (ES)
- Universidad de Sevilla (ES)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2024-08-05
- DOI
- https://doi.org/10.3389/fimmu.2024.1433304
- Citations
- 3
- Primary Topic
- Celiac Disease Research and Management
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- Centro para el Desarrollo Tecnológico Industrial
- Agencia Estatal de Investigación