Optimizing first-line TKI treatment efficacy in PD-L1-positive EGFR-mutated NSCLC: the impact of antiangiogenic agents

For PD-L1-positive patients, combined antiangiogenic treatments and immunotherapy can significantly improve survival outcomes. In contrast, PD-L1-negative patients show less benefit from these therapies, highlighting the greater efficacy of these treatments in PD-L1-positive individuals.

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Publication Details

Journal
Frontiers in Pharmacology
Published
2024-08-05
DOI
https://doi.org/10.3389/fphar.2024.1391972
Citations
2
Primary Topic
Lung Cancer Treatments and Mutations
Type
article
Field-Weighted Citation Impact
0.84
Controls
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article

Optimizing first-line TKI treatment efficacy in PD-L1-positive EGFR-mutated NSCLC: the impact of antiangiogenic agents

Chongya Zhai, Hongming Pan, Pan Yang, Cheng Cheng et al.
2 citations
Frontiers in Pharmacology
Lung Cancer Treatments and Mutations
0.84
article

Optimizing first-line TKI treatment efficacy in PD-L1-positive EGFR-mutated NSCLC: the impact of antiangiogenic agents

Chongya Zhai, Hongming Pan, Pan Yang, Cheng Cheng, Xuanhong Jin, Xinyu Zhu, Liangkun You, Hangchen Shen, Kailai Yin
article en
2 citations

Abstract

For PD-L1-positive patients, combined antiangiogenic treatments and immunotherapy can significantly improve survival outcomes. In contrast, PD-L1-negative patients show less benefit from these therapies, highlighting the greater efficacy of these treatments in PD-L1-positive individuals.

Frontiers in PharmacologyVol. 15
Wenzhou Medical University (CN), Sir Run Run Shaw Hospital (CN), Zhejiang Cancer Hospital (CN), Zhejiang University (CN)
Good health and well-being
Openalex Percentile: Top 25%
Lung Cancer Treatments and Mutations
0.84
DOIOpen Access PDFOpenAlex
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Optimizing first-line TKI treatment efficacy in PD-L1-positive EGFR-mutated NSCLC: the impact of antiangiogenic agents — Chongya Zhai, Hongming Pan, et al. · Frontiers in Pharmacology (2024) | TGRS Research Map | TGRS