Bone mineral density: Comparison between women under hormone replacement therapy with Turner syndrome or idiopathic premature ovarian insufficiency
TS patients had a lower BMD at baseline than idiopathic POI patients, at both spinal and femoral levels. Over time, on HRT, a significant gain in vertebral BMD was observed in patients with TS, compared with a loss of BMD in patients with idiopathic POI. We hypothesized that earlier initiation and longer duration of HRT played an important role in this finding. Long-term prospective follow-up to assess the incidence of fractures in TS would be useful.
Authors
- Jerome Dulon
- Zeina Chakhtoura (ORCID: https://orcid.org/0009-0009-9109-560X)
- Lisa Belin (ORCID: https://orcid.org/0000-0002-7628-6629)
- Isabelle Téjédor
- Charlotte Nelis
- Anne Bachelot
Institutions
- Inserm (FR)
- Institut de Mathématiques de Jussieu-Paris Rive Gauche (FR)
- Sorbonne Université (FR)
- Pitié-Salpêtrière Hospital (FR)
- Institut Pierre Louis d‘Épidémiologie et de Santé Publique (FR)
- Hôpital Charles-Foix (FR)
Publication Details
- Journal
- Annales d Endocrinologie
- Published
- 2024-08-05
- DOI
- https://doi.org/10.1016/j.ando.2024.07.004
- Citations
- 1
- Primary Topic
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Type
- article
- Field-Weighted Citation Impact
- 0.55