Apigenin’s Health Benefits in Kidney Disease: Pharmacological Insights and Future Perspectives

The incidence of kidney diseases is increasing globally, posing a serious threat to human health. Studies have shown that apigenin, a natural dietary flavonoid with multiple bioactivities, may be effective in protecting the kidneys and treating a variety of kidney diseases. This review collates and discusses the available evidence on the therapeutic effects of apigenin on common kidney diseases. In addition, the specific molecular mechanisms by which apigenin exerts its renoprotective effects are described, which informs further research and clinical nutritional applications of apigenin in the field of renal diseases.