Physiological effects and safety of bed verticalization in patients with acute respiratory distress syndrome
Verticalization to 90° is feasible in ARDS patients, improving EELV and oxygenation up to 30°, likely due to alveolar recruitment and blood flow redistribution. However, there is a risk of overdistension and hemodynamic instability beyond 30°, necessitating individualized bed angles based on clinical situations. Trial registration ClinicalTrials.gov registration number NCT04371016 , April 24, 2020.
Authors
- Jean-Étienne Bazin (ORCID: https://orcid.org/0000-0001-5333-570X)
- Gauthier Arpajou
- Jules Audard
- Matthieu Jabaudon (ORCID: https://orcid.org/0000-0002-8121-1680)
- Thomas Godet
- Bruno Pereira (ORCID: https://orcid.org/0000-0003-3778-7161)
- Sophie Cayot (ORCID: https://orcid.org/0000-0002-2924-4282)
- Louis Bouchant
- Lucie Aupetitgendre
- Camille Verlhac
- Raïko Blondonnet (ORCID: https://orcid.org/0000-0001-9881-8422)
- Emmanuel Futier (ORCID: https://orcid.org/0000-0002-6454-271X)
- Lucile Borao
- Jean‐Michel Constantin
- Renaud Guérin
Institutions
- Centre National de la Recherche Scientifique (FR)
- Inserm (FR)
- Université Clermont Auvergne (FR)
- Sorbonne Université (FR)
- Assistance Publique – Hôpitaux de Paris (FR)
- University of Clermont Auvergne (FR)
- Sigma Clermont (FR)
- Centre Hospitalier Universitaire de Clermont-Ferrand (FR)
- Clermont Université (FR)
- Institut Génétique, Reproduction et Développement (FR)
Publication Details
- Journal
- Critical Care
- Published
- 2024-08-05
- DOI
- https://doi.org/10.1186/s13054-024-05013-y
- Citations
- 9
- Primary Topic
- Respiratory Support and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 3.77