Atherosclerosis quantification and cardiovascular risk: the ISCHEMIA trial
In ISCHEMIA, total plaque volume was associated with cardiovascular death or myocardial infarction. In this highly diseased, high-risk population, enhanced assessment of atherosclerotic burden using AI-QCT-derived measures of plaque volume and composition modestly improved event prediction.
Authors
- Jonathon A Leipsic (ORCID: https://orcid.org/0000-0002-6133-8334)
- Tami Crabtree (ORCID: https://orcid.org/0000-0001-6367-8140)
- John A. Spertus (ORCID: https://orcid.org/0000-0002-2839-2611)
- Daniel B. Mark (ORCID: https://orcid.org/0000-0001-6340-8087)
- G.B. John Mancini (ORCID: https://orcid.org/0000-0002-2419-1476)
- James K. Min (ORCID: https://orcid.org/0000-0001-8812-7388)
- Leslee J. Shaw (ORCID: https://orcid.org/0000-0003-1268-1491)
- Nick S. Nurmohamed (ORCID: https://orcid.org/0000-0001-9045-6009)
- Robert Donnino (ORCID: https://orcid.org/0000-0003-3523-6235)
- James P. Earls (ORCID: https://orcid.org/0000-0001-6343-3661)
- Gregg W. Stone (ORCID: https://orcid.org/0000-0002-3416-8210)
- David J. Maron (ORCID: https://orcid.org/0000-0002-4867-8588)
- Jonathan Newman (ORCID: https://orcid.org/0000-0001-6855-7305)
- Mandeep S. Sidhu (ORCID: https://orcid.org/0000-0001-6440-8492)
- Sripal Bangalore (ORCID: https://orcid.org/0000-0001-9485-0652)
- Rebecca Anthopolos (ORCID: https://orcid.org/0000-0002-7251-7792)
- William E. Boden (ORCID: https://orcid.org/0000-0001-7145-8084)
- Cameron John Hague (ORCID: https://orcid.org/0000-0001-9765-3435)
- Bernard Chaitman (ORCID: https://orcid.org/0000-0002-9216-5317)
- Peter H. Stone (ORCID: https://orcid.org/0000-0001-6031-3699)
- Matthew Jay Budoff (ORCID: https://orcid.org/0000-0002-9616-1946)
- Judith S. Hochman (ORCID: https://orcid.org/0000-0002-5889-5981)
- Jeffrey S. Berger (ORCID: https://orcid.org/0000-0001-8216-4647)
- Sean M. O’Brien
- Harmony R Reynolds
Institutions
- Boston University (US)
- Brigham and Women's Hospital (US)
- University of British Columbia (CA)
- George Washington University (US)
- VA Boston Healthcare System (US)
- Clinical Research Institute (US)
- VA New England Healthcare System (US)
- Los Angeles Biomedical Research Institute (US)
- Comprehensive Cardiovascular (US)
- Amsterdam University Medical Centers (NL)
- BC Innovation Council (CA)
- New York University (US)
- University of Missouri–Kansas City (US)
- Albany Medical Center Hospital (US)
- Vrije Universiteit Amsterdam (NL)
- University of Amsterdam (NL)
- Stanford University (US)
- Icahn School of Medicine at Mount Sinai (US)
Publication Details
- Journal
- European Heart Journal
- Published
- 2024-08-05
- DOI
- https://doi.org/10.1093/eurheartj/ehae471
- Citations
- 61
- Primary Topic
- Cardiac Imaging and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 24.66
Funders
- National Heart, Lung, and Blood Institute