Outcomes After Definitive Surgery for Spinal and Sacral Chordoma in 101 Patients Over 20 Years
Surgeons must often weigh the pros and cons of en bloc resection and sacrificing important but affected native tissues. Our findings can provide a benchmark for counseling patients with spinal chordoma. Tumors ≥100 cm 3 appear to have a 5.89-times higher risk of recurrence, mobile spine chordomas have a 7.73 times higher risk, and neoadjuvant radiotherapy confers an 11.1 times lower risk for local recurrence. Patients age ≥65 years at surgery have a 16.70 times higher risk of mortality than those <65 years.
Authors
- Daniel Lubelski (ORCID: https://orcid.org/0000-0002-9403-9509)
- Kristin J. Redmond (ORCID: https://orcid.org/0000-0003-3442-4613)
- Debraj Mukherjee (ORCID: https://orcid.org/0000-0002-5403-8237)
- Jean‐Paul Wolinsky (ORCID: https://orcid.org/0000-0001-5599-4143)
- Timothy F. Witham (ORCID: https://orcid.org/0000-0002-9397-8344)
- Majid Khan (ORCID: https://orcid.org/0000-0002-3807-1387)
- Christian Meyer (ORCID: https://orcid.org/0000-0003-0217-3960)
- Sheng-Fu Larry Lo (ORCID: https://orcid.org/0000-0001-7262-2544)
- Daniel M. Sciubba (ORCID: https://orcid.org/0000-0001-7604-434X)
- John Gross (ORCID: https://orcid.org/0000-0003-4444-0297)
- Tej D. Azad (ORCID: https://orcid.org/0000-0001-7823-4294)
- Abdel‐Hameed Al‐Mistarehi (ORCID: https://orcid.org/0000-0003-4713-8536)
- Landon J. Hansen
- Nicholas Theodore (ORCID: https://orcid.org/0000-0001-5355-2683)
- Yuanxuan Xia (ORCID: https://orcid.org/0000-0001-6152-8392)
- A. Karim Ahmed (ORCID: https://orcid.org/0000-0002-6291-5068)
- Ziya L. Gokaslan (ORCID: https://orcid.org/0000-0003-3187-5697)
- Ali Bydon (ORCID: https://orcid.org/0000-0002-3058-1470)
- Sang Hyub Lee (ORCID: https://orcid.org/0000-0003-2174-9726)
- Pritika Papali
- Chetan Bettegowda
Institutions
- Northwestern University (US)
- Hofstra University (US)
- Johns Hopkins University (US)
- Brown University (US)
- Johns Hopkins Medicine (US)
- Johns Hopkins Hospital (US)
Publication Details
- Journal
- Neurosurgery
- Published
- 2024-08-05
- DOI
- https://doi.org/10.1227/neu.0000000000003130
- Citations
- 8
- Primary Topic
- Bone Tumor Diagnosis and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 3.76