Transplantation of miR-145a-5p modified M2 type microglia promotes the tissue repair of spinal cord injury in mice

These findings indicate that transplantation of miR-145a-5p modified M2 microglia has more therapeutic potential for SCI than M2 microglia transplantation from epigenetic perspective.

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Publication Details

Journal
Journal of Translational Medicine
Published
2024-08-05
DOI
https://doi.org/10.1186/s12967-024-05492-1
Citations
11
Primary Topic
Spinal Cord Injury Research
Type
article
Field-Weighted Citation Impact
4.67

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article

Transplantation of miR-145a-5p modified M2 type microglia promotes the tissue repair of spinal cord injury in mice

Hong‐Yan Qin, Yangguang Ma, Junlong Zhao, Xueyu Hu et al.
11 citations
Journal of Translational Medicine
Spinal Cord Injury Research
4.67
article

Transplantation of miR-145a-5p modified M2 type microglia promotes the tissue repair of spinal cord injury in mice

Hong‐Yan Qin, Yangguang Ma, Junlong Zhao, Xueyu Hu, Lei Feng, Yiyang Hu, Shi-Qian Liang, Tiaoxia Wei, Fan Fan, Zhe Wang, Penghui Li, Liang Wang
article en
11 citations

Abstract

These findings indicate that transplantation of miR-145a-5p modified M2 microglia has more therapeutic potential for SCI than M2 microglia transplantation from epigenetic perspective.

Journal of Translational MedicineVol. 22(1)
Xijing Hospital (CN), Air Force Medical University (CN)
National Natural Science Foundation of China, Natural Science Foundation of Shaanxi Province, Shaanxi Key Science and Technology Innovation Team Project, Shanxi Provincial Key Research and Development Project, Key Research and Development Projects of Shaanxi Province
Good health and well-being
Openalex Percentile: Top 5%
Spinal Cord Injury Research
4.67
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