Implementation of a MSRE ddPCR method for the detection of methylated <i>WIF1</i> and <i>NPY</i> genes in colorectal cancer patients
We showed that this method is robust and sensitive also allowing the monitoring of CRC disease progression when applied to circulating free DNA samples from liquid biopsies, proving to be a fast and easy to implement assay to be used for the monitoring of the methylation pattern of clinically relevant target genes.
Authors
- Omar Perbellini (ORCID: https://orcid.org/0000-0002-8278-8916)
- Luca Trentin (ORCID: https://orcid.org/0000-0002-7447-2946)
- Alice Rossi (ORCID: https://orcid.org/0000-0001-6601-7663)
- Francesca Simionato (ORCID: https://orcid.org/0000-0001-5497-2866)
- Elena Lazzari
- Debora Basile (ORCID: https://orcid.org/0000-0003-1457-2272)
- Filomena Graziani (ORCID: https://orcid.org/0000-0002-6988-3169)
- Alessandro Cappetta
- Giuseppe Aprile (ORCID: https://orcid.org/0000-0003-2007-4077)
- Elena Fietta
- E S d'Amore
Institutions
- AULSS 2 Marca Trevigiana (IT)
- Nuovo Ospedale San Giovanni di Dio (IT)
- Ospedale San Bortolo (IT)
Publication Details
- Journal
- Tumori Journal
- Published
- 2024-08-05
- DOI
- https://doi.org/10.1177/03008916241261675
- Primary Topic
- Epigenetics and DNA Methylation
- Type
- article
- Field-Weighted Citation Impact
- 0.00