Human esophageal cancer stem-like cells escape the cytotoxicity of natural killer cells via down-regulation of ULBP-1
This study reveals that esophageal CSCs are more resistant to NK cells through down-regulation of ULBP-1 and provides a promising approach to promote the activity of NK cells targeting esophageal CSCs.
Authors
- Mengxing Guo
- Kaiyuan Ni (ORCID: https://orcid.org/0000-0002-8152-6746)
- Kai Zhang (ORCID: https://orcid.org/0000-0002-7021-5395)
- Bo Tang (ORCID: https://orcid.org/0000-0002-3568-6925)
- Yi Zhang (ORCID: https://orcid.org/0000-0001-9861-4681)
- Lan Huang (ORCID: https://orcid.org/0000-0001-6556-4067)
- Yujia Zhai (ORCID: https://orcid.org/0000-0003-4697-5797)
Institutions
- First Affiliated Hospital of Zhengzhou University (CN)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2024-08-05
- DOI
- https://doi.org/10.1186/s12967-024-05549-1
- Citations
- 4
- Primary Topic
- Immune Cell Function and Interaction
- Type
- article
- Field-Weighted Citation Impact
- 0.96
Funders
- National Natural Science Foundation of China