Deciphering the enigma of Lassa virus transmission dynamics and strategies for effective epidemic control through awareness campaigns and rodenticides

This study aims to formulate a mathematical framework to examine how the Lassa virus spreads in humans of opposite genders. The stability of the model is analyzed at an equilibrium point in the absence of the Lassa fever. The model's effectiveness is evaluated using real-life data, and all the parameters needed to determine the basic reproduction number are estimated. Sensitivity analysis is performed to pinpoint the crucial parameters significantly influencing the spread of the infection. The interaction between threshold parameters and the basic reproduction number is simulated. Control theory is employed to devise and evaluate strategies, such as awareness campaigns, advocating condom usage, and deploying rodenticides to reduce the possibility of virus transmission efficiently.

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Publication Details

Journal
Scientific Reports
Published
2024-08-05
DOI
https://doi.org/10.1038/s41598-024-68600-7
Citations
11
Primary Topic
Viral Infections and Outbreaks Research
Type
article
Field-Weighted Citation Impact
4.28

Funders

Controls
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article

Deciphering the enigma of Lassa virus transmission dynamics and strategies for effective epidemic control through awareness campaigns and rodenticides

Khaled A. Gepreel, Aziz Ullah Awan, Haneen Hamam, Muhammad Ozair et al.
11 citations
Scientific Reports
Viral Infections and Outbreaks Research
4.28
article

Deciphering the enigma of Lassa virus transmission dynamics and strategies for effective epidemic control through awareness campaigns and rodenticides

Khaled A. Gepreel, Aziz Ullah Awan, Haneen Hamam, Muhammad Ozair, Shafiullah Niazai, Yasir Ramzan, Takasar Hussain
article en
11 citations

Abstract

This study aims to formulate a mathematical framework to examine how the Lassa virus spreads in humans of opposite genders. The stability of the model is analyzed at an equilibrium point in the absence of the Lassa fever. The model's effectiveness is evaluated using real-life data, and all the parameters needed to determine the basic reproduction number are estimated. Sensitivity analysis is performed to pinpoint the crucial parameters significantly influencing the spread of the infection. The interaction between threshold parameters and the basic reproduction number is simulated. Control theory is employed to devise and evaluate strategies, such as awareness campaigns, advocating condom usage, and deploying rodenticides to reduce the possibility of virus transmission efficiently.

Scientific ReportsVol. 14(1)
COMSATS University Islamabad (PK), University of the Punjab (PK), Taif University (SA), Umm al-Qura University (SA)
Taif University
Good health and well-being
Openalex Percentile: Top 5%
Viral Infections and Outbreaks Research
4.28
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Deciphering the enigma of Lassa virus transmission dynamics and strategies for effective epidemic control through awareness campaigns and rodenticides — Khaled A. Gepreel, Aziz Ullah Awan, et al. · Scientific Reports (2024) | TGRS Research Map | TGRS