Inflammatory breast cancer microenvironment repertoire based on DNA methylation data deconvolution reveals actionable targets to enhance the treatment efficacy

Our findings underscored cell subsets that distinguished patients with better survival and dysregulated markers potentially actionable through combinations of immunotherapy and epigenetic drugs.

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Publication Details

Journal
Journal of Translational Medicine
Published
2024-08-05
DOI
https://doi.org/10.1186/s12967-024-05553-5
Citations
6
Primary Topic
Cancer-related molecular mechanisms research
Type
article
Field-Weighted Citation Impact
1.71

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article

Inflammatory breast cancer microenvironment repertoire based on DNA methylation data deconvolution reveals actionable targets to enhance the treatment efficacy

Naiade Calanca, Roberto César Pereira Lima‐Júnior, Milena Botelho Pereira Soares, Flávia Lima Costa Faldoni et al.
6 citations
Journal of Translational Medicine
Cancer-related molecular mechanisms research
1.71
article

Inflammatory breast cancer microenvironment repertoire based on DNA methylation data deconvolution reveals actionable targets to enhance the treatment efficacy

Naiade Calanca, Roberto César Pereira Lima‐Júnior, Milena Botelho Pereira Soares, Flávia Lima Costa Faldoni, Sílvia Regina Rogatto, Deysi Viviana Tenazoa Wong, Fábio Albuquerque Marchi, Cláudia Aparecida Rainho, Cristiano Pádua Souza, Bianca Elen de Souza Alves, Jeferson Santos Souza
article en
6 citations

Abstract

Our findings underscored cell subsets that distinguished patients with better survival and dysregulated markers potentially actionable through combinations of immunotherapy and epigenetic drugs.

Journal of Translational MedicineVol. 22(1)
Serviço Nacional de Aprendizagem Industrial (BR), University of Southern Denmark (DK), Universidade de São Paulo (BR), Universidade Federal do Ceará (BR), Instituto do Câncer do Estado de São Paulo (BR), Hospital de Câncer de Barretos (BR), Lillebaelt Hospital (DK), Fundação Oswaldo Cruz (BR), Universidade Estadual Paulista (Unesp) (BR)
Hospital de Câncer de Barretos, Fundação de Amparo à Pesquisa do Estado de São Paulo, Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, Ministério da Ciência, Tecnologia e Inovação, Conselho Nacional de Desenvolvimento Científico e Tecnológico, Fundação Cearense de Apoio ao Desenvolvimento Científico e Tecnológico, Syddansk Universitet, Division of Graduate Education
Good health and well-being
Openalex Percentile: Top 15%
Cancer-related molecular mechanisms research
1.71
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