Overexpression of ESYT3 improves radioimmune responses through activating cGAS-STING pathway in lung adenocarcinoma
In summary, low ESYT3 expression confers resistance to radiotherapy in LUAD, and its overexpression can improve radioimmune responses through activating cGAS-STING-dependent pathway, thus providing an alternative combination therapeutic strategy for LUAD patients.
Authors
- Tenghua Yu (ORCID: https://orcid.org/0000-0001-6346-8573)
- Xing Niu (ORCID: https://orcid.org/0000-0001-8834-792X)
- Peimeng You
- Mingming Luo
- Ying Li (ORCID: https://orcid.org/0000-0002-8899-7313)
- Junyu Li (ORCID: https://orcid.org/0000-0002-2966-7541)
- Bin Xu (ORCID: https://orcid.org/0009-0000-6745-817X)
- Zan Luo
Institutions
- Nanchang University (CN)
- Jiangxi Provincial Cancer Hospital (CN)
- Hubei Cancer Hospital (CN)
- Huazhong University of Science and Technology (CN)
- China Medical University (CN)
Publication Details
- Journal
- Experimental Hematology and Oncology
- Published
- 2024-08-05
- DOI
- https://doi.org/10.1186/s40164-024-00546-y
- Citations
- 11
- Primary Topic
- interferon and immune responses
- Type
- article
- Field-Weighted Citation Impact
- 2.65
Funders
- Wu Jieping Medical Foundation